Supporting Research
for the O-Shot® Procedure

Apply to participate in our on-going research (treatment will be free if accepted) click<--

Runels CE, Melnick H, DeBourbon E., A Pilot Study of the Effect of Localized Injections of Autologous Platelet Rich Plasma (PRP) for the Treatment of Female Sexual Dysfunction. J Women’s Health Care 2014, 3:4
--->>>Click here to read. The introduction explains the science of the O-Shot®

Hersant B, et al, Efficacy of injecting platelet concentrate combined with hyaluronic acid for the treatment of vulvovaginal atrophy in postmenopausal women with history of breast cancer: a phase 2 pilot study. Menopause 2018, Vol 25, No. 10, pp. 1124-1130

Posey K, Runels C, In Office Surgery and Use of Platelet Rich Plasma for Treatment of Vulvar Lichen Sclerosus to Alleviate Painful Sexual Intercourse, Journal of Lower Genital Tract Disease. 2017 Vol 21, #45. S14

Matz, EL: Safety and feasibility of platelet rich fibrin matrix injections for treatment of common urologic conditions Demonstrates O-Shot® methodology could be widely effective for stress incontinence in Women

The Use of PRP in a Gynecology Setting (notice the extensive references at the end of this paper)<--

Neto JB, O-Shot®: O-Shot: Platelet Rich Plasma in Intimate Female Treatment - oshot-platelets-rich-plasma-in-intimate-female-treatment-2167-0420-1000395

O-Shot® for interstitial cystitis<-- 
We have found that inter-vesicular injections are not necessary--we see great results with our usual O-Shot® technique

Chapter 15 of the following medical text book includes a chapter (written by Dr. Runels) about the O-Shot® procedure with references to the research...

Goldstein AT, King M, Runels C, Gloth M, Pfau R, Intradermal injection of autologous platelet-rich plasma for the treatment of vulvar lichen sclerosus. Journal of the American Academy of Dermatology, 2017, 76(1), 158-160 (click to read)

**Platelet-rich plasma (PRP) for the treatment of vulvar lichen sclerosus in a premenopausal woman: A case report (this one with dramatic photos)<<click to read<---.

**Rejuvenation Using Platelet-rich Plasma and Lipofilling for Vaginal Atrophy and Lichen Sclerosus (click to read)<--

** The use of PRP(platelet-rich plasma) in patients affected by genital lichen sclerosus: clinical analysis and results. <--click to read<==

**The first study with biopsies showing benefit from PRP for lichen sclerosus (using the O-Shot® techniques). The dermatopathologists were blinded to the before and after treatments and benefit was shown...
click to read<---(scroll to the next to l