Hello,
Every week I meet with O-Shot® providers for our Journal Club with Pearls & Marketing (JCPM). We go over the newest research on platelet-rich plasma (PRP) and women’s sexual and urinary health, answer members’ clinical questions about real patients, and share what’s working (and what isn’t) in practice. Every session since 2018 is recorded and turned into an edited transcript, more than 180 so far.
Most sessions are for members only. Below are 29 sessions on the topics physicians ask about most, open for anyone to read. Hope this helps. — Charles Runels, MD
Contents
- Female sexual function, arousal, and orgasm (8 sessions)
- Painful sex, dryness, and vulvar skin conditions (6 sessions)
- Childbirth injury, scars, and trauma (4 sessions)
- Bladder, continence, and comparisons (6 sessions)
- PRP science and research (5 sessions)
- Get every session as a member
Female sexual function, arousal, and orgasm
New Definitions of Female Sexual Dysfunction
Journal Club, May 26, 2026. A walk through the two-year consensus review that redefined hypoactive sexual desire disorder, female genital and cognitive arousal disorders, and orgasmic disorder, and what the new definitions mean for treatment.
How Common Is Female Sexual Dysfunction?
Journal Club, Dec 16, 2025. The surprisingly high prevalence of sexual problems in women, plus PRP compared with a magnetic chair for sexual function and stress incontinence.
Measuring Results with the FSFI and FSDS-R
Journal Club, Sep 3, 2024. Why every O-Shot® recipient should complete the Female Sexual Function Index, how it and the Female Sexual Distress Scale are scored, and the research behind them.
Clitoral Anatomy and the O-Shot® Procedure
Journal Club, Oct 3, 2023. What medical school leaves out about the clitoris: the frenulum, the extensive hidden clitoris, and why the distance from urethra to clitoris matters.
The Female Sex Muscles and the Pelvic Floor
Journal Club, Nov 7, 2023. Why sexual function depends on more than the pelvic floor, and how PRP might help muscle regenerate.
Female Ejaculation and the Skene’s Glands
Journal Club, Jun 23, 2026. A member’s question about female ejaculation: what the Skene’s glands do, and why the injection site matters.
Documenting Results and “Orphan Therapeutics”
Journal Club, Apr 2, 2024. How to document results after the O-Shot® and Clitoxin® procedures, off-label prescribing, and why the trademark protects patients.
Persistent Genital Arousal Disorder (PGAD)
Journal Club, May 21, 2024. What PGAD is, how it relates to the Clitoxin® procedure, and whether it has occurred after the O-Shot® or Clitoxin® procedures.
Painful sex, dryness, and vulvar skin conditions
Lichen Sclerosus: Using the O-Shot® Procedure to Help Prevent Cancer
Journal Club, Feb 25, 2025. Methods that may lower the risk of carcinoma in lichen sclerosus, plus an easy way to classify PRP.
PRP for Lichen Sclerosus and Pre-Malignant Conditions
Journal Club, Jul 14, 2026. PRP for oral potentially malignant disorders and lichen sclerosus, cancer fears about “growth,” and testosterone for women.
Dyspareunia and Lichen Planus: PRP vs. the Usual Treatments
Journal Club, Jun 3, 2025. The O-Shot® procedure compared with estrogen cream for painful sex from dryness, PRP compared with corticosteroids for lichen planus, and a review of treatment options for incontinence.
PRP, Breast Cancer, and Painful Sex After Treatment
Journal Club, Nov 16, 2024. Could PRP help treat or prevent breast cancer? Also, the O-Shot® procedure for dyspareunia after breast cancer.
“Ozempic Vulva” and Lichen Sclerosus
Journal Club, Feb 17, 2026. The O-Shot® procedure for vulvar volume loss after GLP-1 weight loss, and for lichen sclerosus.
Multiple Sclerosis, Incontinence, and the O-Shot® Procedure
Journal Club, Oct 29, 2024. The ignored research on multiple sclerosis and urinary incontinence, and where the O-Shot® procedure fits.
Childbirth injury, scars, and trauma
Episiotomy Pain, Scarring, and Dyspareunia
Journal Club, Nov 18, 2025. Why PRP and the O-Shot® procedure may help repair and regenerate tissue damaged in childbirth, including friable tissue and wound healing.
Episiotomy Scars, PRP vs. Bone Marrow, and Saline
Journal Club, Sep 1, 2026. Three papers that support what we do, including PRP compared with bone marrow aspirate, and whether saline is really a placebo.
Restoring Function After Female Genital Mutilation
Journal Club, Aug 25, 2021. Research on PRP remodeling scars, how to talk with women who have suffered sexual pain, and a method for restoring function after FGM.
PRP in the Vagina: A Review (and the “Revenge Vagina”)
Journal Club, Nov 11, 2025. A review of PRP used in the vagina, flow restriction to boost PRP, and the celebrity headlines.
Bladder, continence, and comparisons
Stress Urinary Incontinence: the O-Shot® Procedure and Emsella
Journal Club, Mar 29, 2022. A detailed look at treating stress incontinence with the O-Shot® procedure and with Emsella.
Injectables for Urinary Incontinence in Women
Journal Club, Oct 27, 2021. A meta-analysis of injectables for incontinence, incontinence in female athletes, and a study showing O-Shot® methods help.
Interstitial Cystitis, and Vaginal Laser With or Without PRP
Journal Club, Sep 9, 2025. The O-Shot® procedure for interstitial cystitis, and research on vaginal laser with and without PRP.
PRP and Recurrent Urinary Tract Infections
Journal Club, Dec 9, 2025. The antibacterial properties of PRP, chronic hard-to-treat infections, and nerve density loss with aging.
Is the O-Shot® Procedure Better Than Kegels?
Journal Club, Dec 19, 2023. Why Kegels work better combined with the O-Shot® procedure, and how the procedure was conceived.
G-Shot® vs. O-Shot®: What’s the Difference?
Journal Club, Aug 1, 2018. Why the difference matters to patients, the FDA and “vaginal rejuvenation,” and genital mismatch vs. vaginal laxity.
PRP science and research
PRP for Scars, and PRP vs. PRF
Journal Club, Aug 11, 2026. PRP for scarring of the face and elsewhere, ten years of search trends for PRP, and how PRP compares with PRF.
PRP vs. PRF, Exercise, and Activation with Calcium Chloride
Journal Club, Sep 8, 2021. How PRP and PRF differ, how exercise affects PRP, and when to activate with calcium chloride.
Telocytes, and When Platelet-Poor Plasma Wins
Journal Club, Jan 24, 2024. How telocytes fit in regeneration, where platelet-poor plasma can outperform PRP, and PRP for vesicovaginal fistula.
Autologous Exosomes and Platelet Embedment
Journal Club, Nov 5, 2024. Autologous exosomes, and how platelets embed when using a gel kit.
Thousands of Studies on PRP for Gynecologic Problems
Journal Club, Sep 2, 2025. Scoping reviews covering more than 3,600 research papers on PRP for women’s gynecologic problems.
Get every session as a member
Members get the live Journal Club every week, the full archive of every session since 2018, the step-by-step O-Shot® training, and a listing in the provider directory. Learn about O-Shot® training and apply here, or read the O-Shot® training FAQ.
